A small RNA response at DNA ends in Drosophila

Small RNAs have been implicated in numerous cellular processes, including effects on chromatin structure and the repression of transposons. We describe the generation of a small RNA response at DNA ends in Drosophila that is analogous to the recently reported double-strand break (DSB)-induced RNAs or Dicer- and Drosha-dependent small RNAs in Arabidopsis and vertebrates. Active transcription in the vicinity of the break amplifies this small RNA response, demonstrating that the normal messenger RNA contributes to the endogenous small interfering RNAs precursor. The double-stranded RNA precursor forms with an antisense transcript that initiates at the DNA break. Breaks are thus sites of transcription initiation, a novel aspect of the cellular DSB response. This response is specific to a double-strand break since nicked DNA structures do not trigger small RNA production. The small RNAs are generated independently of the exact end structure (blunt, 3′- or 5′-overhang), can repress homologous sequences in trans and may therefore—in addition to putative roles in repair—exert a quality control function by clearing potentially truncated messages from genes in the vicinity of the break

Implications of automatic photon quenching on compact gamma-ray sources

Aims: We investigate photon quenching in compact non-thermal sources. This involves photon-photon annihilation and lepton synchrotron radiation in a network that can become non-linear. As a result the gamma-ray luminosity of a source cannot exceed a critical limit that depends only on the radius of the source and on the magnetic field. Methods: We perform analytic and numerical calculations that verify previous results and extend them so that the basic properties of photon quenching are investigated. Results: We apply the above to the 2006 TeV observations of quasar 3C279 and obtain the parameter space of allowed values for the radius of the emitting source, its magnetic field strength and the Doppler factor of the flow. We argue that the TeV observations favour either a modest Doppler factor and a low magnetic field or a high Doppler factor and a high magnetic field.Comment: 10 pages, 12 figures, accepted for publication in Astronomy and Astrophysic

Conversion of relativistic pair energy into radiation in the jets of active galactic nuclei

It is generally accepted that relativistic jet outflows power the nonthermal emission from active galactic nuclei (AGN). The composition of these jets -- leptonic versus hadronic -- is still under debate. We investigate the microphysical details of the conversion process of the kinetic energy in collimated relativistic pair outflows into radiation through interactions with the ambient interstellar medium. Viewed from the coordinate system comoving with the pair outflow, the interstellar protons and electrons represent a proton-electron beam propagating with relativistic speed in the pair plasma. We demonstrate that the beam excites both electrostatic and low-frequency magnetohydrodynamic Alfven-type waves via a two-stream instability in the pair background plasma, and we calculate the time evolution of the distribution functions of the beam particles and the generated plasma wave turbulence power spectra. For standard AGN jet outflow and environment parameters we show that the initial beam distributions of interstellar protons and electrons quickly relax to plateau-distributions in parallel momentum, transferring thereby one-half of the initial energy density of the beam particles to electric field fluctuations of the generated electrostatic turbulence. On considerably longer time scales, the plateaued interstellar electrons and protons will isotropise by their self-generated transverse turbulence and thus be picked-up in the outflow pair plasma. These longer time scales are also characteristic for the development of transverse hydromagnetic turbulence from the plateaued electrons and protons. This hydromagnetic turbulence upstream and downstream is crucial for diffusive shock acceleration to operate at external or internal shocks associated with pair outflows.Comment: A&A in pres

Timing Signatures of the Internal-Shock Model for Blazars

We investigate the spectral and timing signatures of the internal-shock model for blazars. For this purpose, we develop a semi-analytical model for the time-dependent radiative output from internal shocks arising from colliding relativistic shells in a blazar jet. The emission through synchrotron and synchrotron-self Compton (SSC) radiation as well as Comptonization of an isotropic external radiation field are taken into account. We evaluate the discrete correlation function (DCF) of the model light curves in order to evaluate features of photon-energy dependent time lags and the quality of the correlation, represented by the peak value of the DCF. The almost completely analytic nature of our approach allows us to study in detail the influence of various model parameters on the resulting spectral and timing features. This paper focuses on a range of parameters in which the gamma-ray production is dominated by Comptonization of external radiation, most likely appropriate for gamma-ray bright flat-spectrum radio quasars (FSRQs) or low-frequency peaked BL Lac objects (LBLs). In most cases relevant for FSRQs and LBLs, the variability of the optical emission is highly correlated with the X-ray and high-energy (HE: > 100 MeV) gamma-ray emission. Our baseline model predicts a lead of the optical variability with respect to the higher-energy bands by 1 - 2 hours and of the HE gamma-rays before the X-rays by about 1 hour. We show that variations of certain parameters may lead to changing signs of inter-band time lags, potentially explaining the lack of persistent trends of time lags in most blazars.Comment: Accepted for publication in Ap

Temporal signatures of leptohadronic feedback mechanisms in compact sources

The hadronic model of Active Galactic Nuclei and other compact high energy astrophysical sources assumes that ultra-relativistic protons, electron-positron pairs and photons interact via various hadronic and electromagnetic processes inside a magnetized volume, producing the multiwavelength spectra observed from these sources. A less studied property of such systems is that they can exhibit a variety of temporal behaviours due to the operation of different feedback mechanisms. We investigate the effects of one possible feedback loop, where \gamma-rays produced by photopion processes are being quenched whenever their compactness increases above a critical level. This causes a spontaneous creation of soft photons in the system that result in further proton cooling and more production of \gamma-rays, thus making the loop operate. We perform an analytical study of a simplified set of equations describing the system, in order to investigate the connection of its temporal behaviour with key physical parameters. We also perform numerical integration of the full set of kinetic equations verifying not only our analytical results but also those of previous numerical studies. We find that once the system becomes `supercritical', it can exhibit either a periodic behaviour or a damped oscillatory one leading to a steady state. We briefly point out possible implications of such a supercriticality on the parameter values used in Active Galactic Nuclei spectral modelling, through an indicative fitting of the VHE emission of blazar 3C 279.Comment: 19 pages, 20 figures, accepted for publication in MNRA

A New Model for the Hard Time Lags in Black Hole X-Ray Binaries

The time-dependent Comptonized output of a cool soft X-ray source drifting inward through an inhomogeneous hot inner disk or corona is numerically simulated. We propose that this scenario can explain from first principles the observed trends in the hard time lags and power spectra of the rapid aperiodic variability of the X-ray emission of Galactic black-hole candidates.Comment: 10 pages, including 2 figures; uses epsf.sty, rotate.sty; accepted for ApJ Letter

The long-term optical spectral variability of BL Lacertae

We present the results from a study of the long-term optical spectral variations of BL Lacertae, using the long and well-sampled B and R-band light curves of the Whole Earth Blazar Telescope (WEBT) collaboration, binned on time intervals of 1 day. The relation between spectral slope and flux (the spectrum gets bluer as the source flux increases) is well described by a power-law model, although there is significant scatter around the best-fitting model line. To some extent, this is due to the spectral evolution of the source (along well-defined loop-like structures) during low-amplitude events, which are superimposed on the major optical flares, and evolve on time scales of a few days. The "bluer-when-brighter" mild chromatism of the long-term variations of the source can be explained if the flux increases/decreases faster in the B than in the R band. The B and R-band variations are well correlated, with no significant, measurable delays larger than a few days. On the other hand, we find that the spectral variations lead those in the flux light curves by ~ 4 days. Our results can be explained in terms of Doppler factor variations due to changes in the viewing angle of a curved and inhomogeneous emitting jet.Comment: 7 pages, 5 figures, accepted for publication in A&